How to get really sick, weak muscles, and lots of fat:
1. Grow a tumor that makes you produce too much cortisol.
2. Complain about symptoms to doctor.
3. Get laughed out of doctor's office with orders to diet and exercise.
4. Diet and exercise increase cortisol production, making you sicker, fatter, and weakening your thigh and upper arm muscles.
5. Repeat steps 2-4 until you die prematurely or a doctor finally decides to test you for Cushing's Disease/Syndrome.