I am a 29-year-old female currently undergoing testing for Cushing's syndrome and awaiting my first Endo visit. My husband is also testing for Cushing's. So we make quite a pair!
I work in an endocrinology-related field. I guess in part I originally went into medical research to figure out why I was overweight (now obese) despite eating healthier than my friends and playing tons of sports. I just assumed it was simply genetics (well maybe it is still partially genetics).
My one and only cortisol test so far was moderately high: 4 pm serum cortisol was 21.4 ug/dl (normal 3-16.7).
Over the years, many symptoms were overlooked (or blamed on me) by doctors, the most obvious being the weight gain. I have gained about 100 lbs since I was 17-years-old, usually in 10-30 lb spurts.
In college, my now-husband would tease me about my growing hump (buffalo hump), which he blamed on my bad posture. I sweat a lot and am constantly warm. For the last few years I have been waking up at night to pee, which in 2009 my gynecologist blamed on my abdominal weight gain.
The recent severe fatigue, muscle weakness, joint pain and muscle pain have started to make life miserable and are what motivated me to finally ask the doctor about Cushing?s. I get tired with simple things like taking a shower. My hands hurt so bad it is difficult to do my job, my knees make it hard to climb stairs, and my swollen feet make it painful to stand (diuretics only help slightly). My back, neck and shoulders are usually sore, I get strong flank/mid-back pain around my kidneys/adrenal glands, and I get headaches almost every day.
Some Other Symptoms:
Frequent Infections (especially sinus infections), poor wound healing
Translucent skin with visible blue veins
Stretch marks all over, especially abdomen and arms (large, pink or white) and spider veins
Easy bruising and skin tears easily
Itchy, dry skin, crawling feeling on skin
Irregular periods and low libido
Memory problems (short-term and long-term)
Lack of concentration and easily distracted, brain fuzzy, more difficulty thinking
Anxiety/worrying, irritable, moody, mild depression
Stabbing abdominal pain off and on
Low Vitamin D
Fat accumulation in supraclavicular fat pads, thicker neck
Round moon face, often gets flushed (red)
Dizziness and tinnitus (ringing in ears)
Increased thirst and urination (especially at night) and dry mouth
Insomnia: staying up later, more difficulty falling asleep, waking up a lot
Tingling/numbness in hands and feet
Muscles twitching and cramping, hands shaking sometimes
Diarrhea, hiccups, occasional constipation, nausea, acid reflux
Hair on face, breasts and stomach, and acne
Difficulty drawing blood (small wiggly veins), pulse hard to feel
High blood pressure (new)
High cholesterol and triglycerides
Low-normal testosterone and DHEA-SO4
TSH: 3.3 (was 2.6 in June, 2010)
Feet have grown from size 10.5 to 12 since college
High White Blood Cell (WBC) count (high neutrophils)
High Alkaline Phosphatase
Hard to focus eyes, vision getting worse, pupils dilated and off-center