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lydia

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About lydia

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  1. Lydi,

    You've been gone too long. Hope you're safe.

    Captain Pugwash, King of Pirates.

  2. still alive, somewhat. Just emerging again from bad bad time. Keto made me alive again. Will be off line for some time soon, going to emigrate next week to Bonaire (next to Curacao and Aruba)

    My house has no internet yet, actually it has no furniture or even a spoon in it LOL

    Will get back once I can be on line.

    But then on line on paradise island:)

    hugs to you Jo.

  3. how are you lydia long time no see ? hope you are well im not on the site often myself now tc jo x

  4. :( (((hugs)) Lydia I am praying that the doctors will stop being stupid & lazy and help you
  5. meant, madam, you are still looking cushie.

    Ah well..I am eating my keto, on own initiative, untill I have no more. That's it. They denied my second tumor, because 'they"did not see it on their lame tesla 1.

  6. to Dave and others who may wonder:

    Hello my pirate,

    have been away, hiding in social anxiety and depression land.

    Since testing me one again for cushings, they took my keto away and I went back into the cave of the wounded cushie.

    Nothing happened yet, messed up tests, yet the results are believed and please madam, come back in a year or so, because you still loo...

  7. How are you lydia ? i hope you are well "big hope" i gave up with it all for a while but thanks for the advice on the t3 as all my odema has almost gone pity about the rest anyway tc jo xx

  8. Lydi...How are you?

  9. Yes same as immodium. It was the same immodium that sent me on a search, because my husband needed it in India and went sleeping all day and night, so I wondered if it lowered cortisol. So I googled and found the above results. so yes, it must interfere with testing then big time.
  10. I had the same thoughts as you.. now I wonder, if GFR is still low after cushing's is gone, how do they handle that? edit..oooooh, last time my endo who does the GFR research in cushing's..gave me amlodipine, ohhh, seems to make the GFR better or at least stop it from going down more.
  11. Found other article, more info on the GFR and cushing's testing: Because plasma free cortisol is filtered through the glomeruli with partial tubular reabsorption, the amount of free cortisol appearing in the urine is theoretically dependent on the glomerular filtration rate. However, the high reliability of using 24-h urinary cortisol excretion for the diagnosis of Cushing syndrome implies that urinary excretion of cortisol is relatively unaffected by renal function. In patients with confirmed Cushing disease and severe renal impairment, the urinary free cortisol excretion rate reportedly is normal despite markedly increased plasma cortisol (4)(5)(6). The relationship between glomerular filtration rate and urinary cortisol excretion has not been documented in patients with different degrees of renal impairment. http://www.clinchem.org/cgi/content/full/50/4/757
  12. yes slight decrease in GFR which normally gets better once hypothyroid is adressed.
  13. googled this and it seems you are on the target! URINARY EXCRETION OF FREE CORTISOL IN IMPAIRED RENAL FUNCTION P. Sederberg-Olsen, C. Binder and H. Kehlet Total cortisol and free, non protein-bound cortisol in plasma and urinary excretion of unconjugated free cortisol were measured during iv infusion of cortisol at varying dose rates in eight patients with impaired renal function. The results showed that free urinary cortisol decreased with decreased glomerular filtration rate (GFR), also compared to free cortisol level in plasma. An increase in free cortisol in plasma had no influence on GFR. It is concluded that determination of free urinary cortisol, otherwise useful in diagnosing Cushing's syndrome, may be of less value in patients with impaired renal function. http://www.eje-online.org/cgi/content/abstract/78/1/86
  14. Yes, seems GFR is typical low in cushing's. There is more abstracts stating it. Glad the info is helpful.
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