NIH Cushing's Clinical Trials

[~MaryO~]

Rank Status Study 1 Recruiting Safety and Efficacy of LCI699 in Cushing's Disease Patients Condition: Cushing Disease Intervention: Drug: LCI699 2 Recruiting Preoperative Bexarotene Treatment for Cushing's Disease Condition: Cushing's Disease Intervention: Drug: Bexarotene 3 Recruiting Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease) Condition: Brain and Central Nervous System Tumors Interventions: Drug: rosiglitazone maleate; Other: laboratory biomarker analysis 4 Unknown ^?Study of Depression, Peptides, and Steroids in Cushing's Syndrome Condition: Cushing's Syndrome Intervention:

5 Recruiting Examination of Brain Serotonin Receptors in Patients With Mood Disorders Conditions: Mood Disorder; Bipolar Disorder; Depression Intervention:

6 Recruiting An Investigation of Pituitary Tumors and Related Hypothalmic Disorders Conditions: Abnormalities; Craniopharyngioma; Cushing's Syndrome; Endocrine Disease; Pituitary Neoplasm Intervention:

7 Recruiting Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion Condition: Cushing's Syndrome Intervention: Drug: Mifepristone 8 Recruiting Anesthesia Management of Retroperitoneal Adrenalectomies Condition: Adrenal Tumors Intervention:

9 Recruiting Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex Conditions: Cushing's Syndrome; Hereditary Neoplastic Syndrome; Lentigo; Neoplasm; Testicular Neoplasm Intervention:

10 Recruiting New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome Condition: Cushing Syndrome Intervention:

11 Recruiting Adolescence, Puberty, and Emotion Regulation Conditions: Mood Disorder; Neurobehavioral Manifestation; Healthy Intervention:

12 Recruiting Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome Conditions: Cushing's Syndrome; Insulin Resistance Intervention: Procedure: Surgery 13 Recruiting Study of Adrenal Gland Tumors Condition: Adrenal Gland Neoplasm Intervention:

14 Not yet recruiting Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome Condition: Adrenal Tumour With Mild Hypercortisolism Intervention: Procedure: Adrenalectomy 15 Recruiting Assessing Fertility Potential in Female Cancer Survivors Condition: History of Cancer Intervention:

16 Recruiting Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin Conditions: Pancreatic Neoplasm; Pituitary Neoplasm; Nelson Syndrome; Ectopic ACTH Syndrome Intervention: Drug: Pasireotide LAR 17 Recruiting Adrenal Tumors - Pathogenesis and Therapy Conditions: Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma Intervention:

18 Recruiting Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma Condition: Pituitary Tumor Intervention:

19 Recruiting Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study) Conditions: Neutropenia; Infection Interventions: Drug: Standard antimicrobial therapy; Biological: Granulocyte transfusions; Drug: G-CFS/dexamethasone; Device: Apheresis machine