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MaryO

Cushing's Testing at NIH

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Rank Status Study 1 Recruiting

Study to Evaluate CORT125134 in Patients With Cushing's Syndrome

Condition: Cushing's Syndrome Intervention: Drug: CORT125134 2 Recruiting

Cushing's Disease Complications

Condition: Cushing's Disease Intervention: Other: Exams and questionnaires 3 Recruiting

The Accuracy of Late Night Urinary Free Cortisol/Creatinine and Hair Cortisol in Cushing's Syndrome Diagnosis

Condition: Cushing Syndrome Intervention:   4 Recruiting

Treatment for Endogenous Cushing's Syndrome

Condition: Endogenous Cushing's Syndrome Intervention: Drug: COR-003 5 Recruiting

Saliva Cortisol Measurement as a Screening Test for Suspicious Cushings Syndrome in Children.

Condition: Cushings Syndrome Intervention: Other: Children refered to the obesity clinic 6 Recruiting

Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease

Condition: Cushing's Disease Intervention: Drug: LCI699 7 Recruiting

Treatment of Cushing's Disease With R-roscovitine

Condition: Cushings Disease Intervention: Drug: R-roscovitine 8 Recruiting

A Study of ATR-101 for the Treatment of Endogenous Cushing's Syndrome

Condition: Cushing Syndrome Interventions: Drug: ATR-101;   Drug: Placebos 9 Recruiting

Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients With Ectopic Cushing Syndrome

Condition: Cushing Syndrome Interventions: Drug: F-DOPA PET Scan;   Drug: Mifepristone;   Drug: Ga-DOTATATE;   Drug: Octreoscan;   Other: CT, MRI 10 Not yet recruiting

Endocrine Cardiomyopathy in Cushing Syndrome: Response to Cyclic GMP PDE5 inhibitOrs

Condition: Cushing's Syndrome Cardiomyopathy Intervention: Drug: Tadalafil 11 Recruiting

Long-term Beneficial Metabolic Effects of Adrenalectomy in Subclinical Cushing's Syndrome of Adrenal Incidentaloma

Condition: Cushing Syndrome Intervention: Procedure: surgery 12 Recruiting

Long Term Safety and Efficacy of Pasireotide s.c. in Patients With Cushing's Disease

Condition: Cushings Disease Intervention: Drug: SOM230 13 Recruiting

New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome

Condition: Cushing Syndrome Interventions: Drug: Pentetreotide;   Drug: 18-F-fluorodeoxyglucose;   Drug: (18F)-L-3,4-dihydroxyophenylalanine (18F-DOPA) 14 Not yet recruiting

Targeting Iatrogenic Cushing's Syndrome With 11β-hydroxysteroid Dehydrogenase Type 1 Inhibition

Condition: Iatrogenic Cushing's Disease Interventions: Drug: AZD4017 and prednisolone;   Drug: Placebo Oral Tablet and prednisolone 15 Not yet recruiting

Assessment of Persistent Cognitive Impairment After Cure of Cushing's Disease

Condition: Cushing's Disease Intervention: Device: Virtual radial task in 3D 16 Recruiting

Biomarker Expression in Patients With ACTH-Dependent Cushing's Syndrome Before and After Surgery

Condition: Cushing's Syndrome Intervention:   17 Recruiting

Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease

Condition: Cushing's Disease Interventions: Drug: osilodrostat;   Drug: osilodrostat Placebo 18 Recruiting

Effects of Metyrapone in Patients With Endogenous Cushing's Syndrome

Condition: Cushing's Syndrome Intervention: Drug: metyrapone 19 Recruiting

Adrenal Venous Sampling in Patients With Overt or Subclinical Cushings Syndrome, and Bilateral Adrenal Tumors

Condition: Cushing Syndrome Intervention: Radiation: Adrenal venous sampling 20 Recruiting

Glycemic Fluctuations in Newly Diagnosed Growth Hormone-Secreting Pituitary Adenoma and Cushing Syndrome Subjects

Condition: Pituitary Adenoma Intervention: Device: continuous glucose monitoring
Rank Status Study 21 Recruiting

Targeted Therapy With Gefitinib in Patients With USP8-mutated Cushing's Disease

Conditions: Cushing's Disease;   Corticotrophin Adenoma Intervention: Drug: Gefitinib 22 Recruiting

Cardiac Steatosis in Cushing's Syndrome

Conditions: Endocrine System Disease;   Cardiovascular Imaging Intervention: Other: 1H magnetic resonance spectroscopy and CMRI 23 Recruiting

Study of Management of Pasireotide-induced Hyperglycemia in Adult Patients With Cushing's Disease or Acromegaly

Conditions: Cushing's Disease;   Acromegaly Interventions: Drug: Pasireotide s.c.;   Drug: Sitagliptin;   Drug: Liraglutide;   Drug: Insulin;   Drug: Pasireotide LAR;   Drug: Metformin 24 Recruiting

Study of Efficacy and Safety of Osilodrostat in Cushing's Syndrome

Conditions: Cushing's Syndrome;   Ectopic Corticotropin Syndrome;   Adrenal Adenoma;   Adrenal Carcinoma;   AIMAH;   PPNAD Intervention: Drug: Osilodrostat 25 Recruiting

Effects of Hormone Stimulation on Brain Scans for Cushing s Disease

Condition: Pituitary Neoplasm Intervention: Drug: Acthrel 26 Recruiting

Does Serum-DXM Increase Diagnostic Accuracy of the Overnight DXM Suppression Test in the Work-up of Cushing's Syndrome?

Conditions: Cushing's Syndrome;   Adrenal Incidentalomas;   Alcoholism;   Obesity Intervention:   27 Recruiting

Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome

Condition: Adrenal Tumour With Mild Hypercortisolism Intervention: Procedure: Adrenalectomy 28 Recruiting

Study of Adrenalectomy Versus Observation for Subclinical Hypercortisolism

Conditions: Hypercortisolism;   Cushing Syndrome Interventions: Procedure: Adrenalectomy;   Other: Observation 29 Not yet recruiting

Dynamic Hormone Diagnostics in Endocrine Disease

Conditions: Adrenal Insufficiency;   Congenital Adrenal Hyperplasia;   Cushing Syndrome;   Growth Hormone Deficiency;   Acromegaly;   Primary Hyperaldosteronism Intervention: Other: 27 hour subcutaneous fluid sampling 30 Recruiting

An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

Conditions: Abnormalities;   Craniopharyngioma;   Cushing's Syndrome;   Endocrine Disease;   Pituitary Neoplasm Intervention:   31 Recruiting

Ga-68-DOTATOC -PET in the Management of Pituitary Tumours

Condition: Pituitary Tumours Intervention: Procedure: Gallium-68 DOTATOC PET 32 Recruiting

Efficacy of Mifepristone in Males With Type 2 Diabetes Mellitus

Conditions: Type 2 Diabetes Mellitus;   Insulin Resistance Interventions: Drug: Mifepristone 600 mg daily;   Drug: Placebo 33 Recruiting

Targeted Therapy With Lapatinib in Patients With Recurrent Pituitary Tumors Resistant to Standard Therapy

Conditions: Pituitary Adenomas;   Prolactinomas Intervention: Drug: Lapatinib 34 Recruiting

Mutations of Glucocorticoid Receptor in Bilateral Adrenal Hyperplasia

Condition: General Glucocorticoid Resistance Intervention: Genetic: blood collection for mutation characterization 35 Recruiting

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

Conditions: Cushing's Syndrome;   Hereditary Neoplastic Syndrome;   Lentigo;   Neoplasm;   Testicular Neoplasm Intervention:   36 Not yet recruiting

Reduction by Pasireotide of the Effluent Volume in High-output Enterostomy in Patients Refractory to Usual Medical Treatment

Condition: Enterostomy Interventions: Drug: Pasireotide;   Drug: Placebo 37 Recruiting

Mifepristone for Breast Cancer Patients With Higher Levels of Progesterone Receptor Isoform A Than Isoform B.

Condition: Breast Cancer Intervention: Drug: Mifepristone 38 Recruiting

SOM230 Ectopic ACTH-producing Tumors

Condition: Ectopic ACTH Syndrome Intervention: Drug: Pasireotide 39 Recruiting

Decreasing Rates of Intraurethral Catheterization Postoperatively in Spine Surgery

Condition: Post-operative Urinary Retention Interventions: Drug: Tamsulosin;   Drug: Placebo 40 Recruiting

Adrenal Tumors - Pathogenesis and Therapy

Conditions: Adrenal Tumors;   Adrenocortical Carcinoma;   Cushing Syndrome;   Conn Syndrome;   Pheochromocytoma Intervention:  
 

 

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