INTRODUCTION
MATERIALS AND METHODS
RESULTS
Demographic data
Preoperative imaging
Table 1.
Values are presented as number (%). Invasion : 0, sella normal; 1, sella focally expanded and tumor ≤10 mm; 2, sella enlarged and tumor ≥10 mm; 3, localized perforation of the sellar floor; 4, diffuse destruction of the sellar floor. Suprasellar extension : A, no suprasellar extension; B, anterior recesses of the third ventricle obliterated; C, floor of the third ventricle grossly displaced with parasellar extension; D, intracranial (intradural) : anterior, middle or middle fossa; E, into/beneath the cavernous sinus (extradural).
NA : not available
Postoperative results
Table 2.
3−6-month remission | Long-term remission | |
---|---|---|
Maximum tumor size | ||
Group 1, 0−5 mm (n=41) | 31 (75.6) | 33 (80.5) |
Group 2, 6−10 mm (n=24) | 22 (91.7) | 22 (91.7) |
Group 3, 10−20 mm (n=20) | 17 (85.0) | 17 (85.0) |
Group 4, >20 mm (n=11) | 4 (36.4) | 7 (63.6) |
p-value | 0.003* | 0.200 |
Knops classification | ||
0 (n=52) | 41 (78.8) | 44 (84.6) |
1 (n=22) | 21 (95.5) | 21 (95.5) |
2 (n=6) | 4 (66.7) | 3 (50.0) |
3 (n=8) | 7 (87.5) | 7 (87.5) |
4 (n=8) | 1 (12.5) | 4 (50.0) |
p-value | <0.001* | 0.010* |
Modified Hardy classification | ||
0 | ||
A (n=41) | 32 (78.0) | 34 (82.9) |
1 | ||
A (n=14) | 12 (85.7) | 12 (85.7) |
2 | ||
E (n=4) | 3 (75.0) | 3 (75.0) |
A (n=5) | 5 (100.0) | 5 (100.0) |
3 | ||
E (n=5) | 2 (40.0) | 2 (40.0) |
A (n=1) | 1 (100.0) | 1 (100.0) |
B (n=2) | 2 (100.0) | 2 (100.0) |
4 | ||
E (n=1) | 0 (0.0) | 0 (0.0) |
A (n=1) | 1 (100.0) | 1 (100.0) |
D (n=1) | 0 (0.0) | 0 (0.0) |
E (n=3) | 1 (33.3) | 3 (100.0) |
p-value | 0.10 | 0.06 |
Pathology result | ||
Corticotropinoma (+) (n=71) | 58 (81.7) | 60 (84.5) |
Corticotropinoma (-) (n=25) | 16 (64.0) | 19 (76.0) |
p-value | 0.07 | 0.30 |
Values are presented as number (%). Invasion : 0, sella normal; 1, sella focally expanded and tumor ≤10 mm; 2, sella enlarged and tumor ≥10 mm; 3, localized perforation of the sellar floor; 4, diffuse destruction of the sellar floor. Suprasellar extension : A, no suprasellar extension; B, anterior recesses of the third ventricle obliterated; D, intracranial (intradural) with anterior, middle, or middle fossa; E, into/beneath the cavernous sinus (extradural).
Day 6: Cushing’s Awareness Challenge 2022
in Cushing's Awareness Day, April 8
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