It may not have been adrenal crisis, but it may have, as Renea, after her BLA, didn't need replacement. She hadn't taken hydro for some year(s), and yet her cortisol was always '0'. The doctors would just scratch their heads.
Renea was 31.
Read more at https://cushingsbios.com/2015/03/30/in-memory-alena-renea-weeks-greenhill/