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Showing results for tags 'relacorilant'.
Hello Mary & dear Cushing’s, I hope you are all doing well during this pandemic... I must tell you I got sick with COVID-19 since January 2021 and I’m still recovering with pneumonia... and I won’t lie if I say it has been the WORST disease I’ve ever had... even worse than my first PANHYPERPITUITARISM with Cushing’s Disease and now with my Cushing’s syndrome relapse... but thanks God I’m alive and recovering. I’m writing here because I found out that the GRACE trial of Relacorilant is delayed due to COVID-19 pandemic and that they are still enrolling participants... so I will le
Corcept Therapeutics is recruiting participants for its Phase 3 clinical trial evaluating relacorilant as a potential treatment for Cushing’s syndrome-related side effects such as high blood pressure and impaired glucose tolerance. Also, findings from the study “A Randomized-Withdrawal, Placebo-Controlled, Phase 3 Study to Assess the Efficacy and Safety of Selective Glucocorticoid Receptor Antagonist, Relacorilant, in Patients with Cushing Syndrome (GRACE Study),” were presented at the 2019 Annual Meeting of the Endocrine Society (ENDO), in New Orleans, Louisiana. In endogenous Cushi
The glucocorticoid receptor antagonist CORT125134 is safe and has shown preliminary signs of efficacy in healthy volunteers participating in a Phase 1 trial, say researchers in England. Their study, “Assessment of Safety, Tolerability, Pharmacokinetics, and Pharmacological Effect of Orally Administered CORT125134: An Adaptive, Double-Blind, Randomized, Placebo-Controlled Phase 1 Clinical Study,” appeared in the journal Clinical Pharmacology in Drug Development.” Cortisol signaling is indirectly controlled by the glucocorticoid receptor (GR). When cortisol binds the GR, the receptor b