Pergolide and Heart Disease

[Guest Rose Marie]

"A recent study at the Mayo Clinic (Mayo Clin Proc, December 2002) entitled "Valvular Heart Disease in Patients Using Pergolide", http://www.mayo.edu/proceedings/2002/dec/7712a1.pdf ?described three patients who were diagnosed as having valvular heart disease while receiving long term therapy with pergolide mesylate. The valve abnormalities bore similarities to the cardiac valve lesions that in 1997 were detected with fenfluramine (fen-phen) and dexfenfluramine. Pergolide mesylate is used to treat patients with Parkinson's disease and restless legs syndrome. An association between pergolide and cardiac valve lesions has not been definitely confirmed. The observations have been reported to FDA and, to date, no advisory has been issued. As your patients return for continuing care, please keep this observation in mind..."

 

http://www.aace.com/pergolide.php

 

Petgolide is also Permax which is used to treat prolactinomas.

http://pituitarysociety.med.nyu.edu/vance1.htm

 

rm

[Guest]

Rose,

 

Thanks for posting this article, I think I am going to show it to my new doctor, if she wants to try the pergolide, I have already been on the parlodel. Found some very interesting things out recently about these medication. First on the PNA website, I was reading again they had an article about, how taking parolodel, or pegolide, for more than 6 months could indeed make the tumor more fibrosis and harder to remove if the tumor needed removed, didn't know this, guess this would be me in this case. Also, now after reading this article I do indeed to bring up the chest pains and the rapid heart beat at times again, just to be on the safe side. I am always told it is costrochondritis (spelling), because they feel since I have autoimmune problems this is what it is, never has anyone wanted to check to see what is happening except one EKG which was normal.

 

Anyhow, thanks for posting this info.

 

How are things your way?

 

Paula