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Herb found ineffective for moderate depression

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Herb found ineffective for moderate depression

NEW YORK, Apr 09 (Reuters Health) - Although promoted as an alternative therapy for depression, the herbal supplement St. John's wort appears ineffective for people with moderate clinical depression, findings from a US study suggest.


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Effect of Hypericum perforatum (St John's Wort) in Major Depressive Disorder  


A Randomized Controlled Trial

Hypericum Depression Trial Study Group


Context  Extracts of Hypericum perforatum (St John's wort) are widely used for the treatment of depression of varying severity. Their efficacy in major depressive disorder, however, has not been conclusively demonstrated.


Objective  To test the efficacy and safety of a well-characterized H perforatum extract (LI-160) in major depressive disorder.


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