Chief Cushie ~MaryO~ Posted March 18, 2008 Chief Cushie Report Share Posted March 18, 2008 http://content.karger.com/ProdukteDB/produ...roduktNr=224036 Advances in the Management of Paediatric Cushing's Disease Martin O. Savage, Li F. Chan, Farhad Afshar, P. Nicholas Plowman, Ashley B. Grossman, Helen L. Storr Departments of Endocrinology, Neurosurgery and Radiotherapy, Barts and the London School of Medicine and Dentistry, London, UK Address of Corresponding Author Horm Res 2008;69:327-333 (DOI: 10.1159/000117388) Key Words * Cushing's disease * Paediatrics * Transsphenoidal surgery * Pituitary radiotherapy Abstract Cushing's disease (CD) is rare in the paediatric age range, but may present a difficult therapeutic challenge. Most paediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. Prior to definitive treatment, a diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of paediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life. Copyright ? 2008 S. Karger AG, Basel Author Contacts Prof. Martin Savage, Department of Endocrinology Barts and the London School of Medicine and Dentistry John Vane Science Centre, Charterhouse Square London EC1M 6BQ (UK) Tel. +44 20 7882 6233, Fax +44 7882 6234, E-Mail m.o.savage@qmul.ac.uk Article Information Received: March 5, 2007 Accepted: October 2, 2007 Published online: March 17, 2008 Number of Print Pages : 7 Number of Figures : 3, Number of Tables : 3, Number of References : 49 Free Abstract Article (Fulltext) Article (PDF 230 KB) Link to comment Share on other sites More sharing options...
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