Jump to content

Cardiovascular consequences of cortisol excess


MaryO

Recommended Posts

  • Chief Cushie

Vascular Health and Risk Management

Issue: Issue 4

Cardiovascular consequences of cortisol excess

 

Judith A Whitworth1, Paula M Williamson1, George Mangos2, John J Kelly2

 

1John Curtin School of Medical Research, Australian National University, Canberra, ACT, Australia; 2Department of Renal Medicine, St George Hospital, Kogarah, NSW, Australia

 

Abstract: Cushing?s syndrome is a consequence of primary or, more commonly, secondary oversecretion of cortisol. Cardiovascular disease is the major cause of morbidity and mortality in Cushing?s syndrome, and excess risk remains even in effectively treated patients. The cardiovascular consequences of cortisol excess are protean and include, inter alia, elevation of blood pressure, truncal obesity, hyperinsulinemia, hyperglycemia, insulin resistance, and dyslipidemia. This review analyses the relationship of cortisol excess, both locally and at tissue level, to these cardiovascular risk factors, and to putative mechanisms for hypertension. Previous studies have examined correlations between cortisol, blood pressure, and other parameters in the general population and in Cushing?s syndrome. This review also details changes induced by short-term cortisol administration in normotensive healthy men.

Keywords: blood pressure, cortisol, Cushing?s syndrome, risk factors

 

 

Purchase this paper now

 

Price: $59 USD

Link to comment
Share on other sites

I realize that this is only an extract, but it doesn't mention Congestive Heart Failure. That's what I had and at the time, the docs indocated that it was caused from the Cushings.

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...