Over 2000 Posts da89165 Posted June 12, 2010 Over 2000 Posts Report Share Posted June 12, 2010 For those of you who are applying for disability benefits, this article gives good data on the quality of life and % of disability for those with adrenal insufficiency. I realize this doesn't necessarily apply to everyone, but if you've had a BLA or have ACTH deficiency, this could be helpful to your case. The last page of this article gives the info I'm talking about. ** The numbers are references to the footnotes at the end of the article......sorry the formating is not so great. "Quality of life, disablility, and prognosis Prospective data10 indicate excess mortality in hypopituitarism, including secondary adrenal insufficiency, mainly due to vascular and respiratory disease. However, deficiencies of other hormonal axes could also contribute. Mortality in patients with primary adrenal insufficiency has not been studied. Nevertheless, life expectancy may be reduced as a consequence of unrecognised adrenal crisis, underlying illness?eg, adrenomyeloneuropathy?and other as yet unidentified causes.4 Despite adequate glucocorticoid and mineralocorticoid replacement, health-related quality of life is greatly impaired in patients with primary65 and secondary adrenal insufficiency.143 Predominant complaints are fatigue, lack of energy, depression, and anxiety.65,69,70 In addition, affected women frequently complain about impaired libido. In a survey of 91 individuals, 50% of patients with primary adrenal insufficiency considered themselves unfit to work and 30% needed household help.144 In another survey of 88 individuals the number of patients who received disablility pensions was two to three times higher than in the general population.65 The adverse effect of chronic adrenal insufficiency on health-related quality of life is comparable to that of congestive heart failure.65 However,fine-tuning of glucocorticoid replacement leaves only a narrow margin for improvement, and changes in timing or dose do not result in improved wellbeing.145,146 Dehydroepiandrosterone (DHEA) replacement in adrenal insufficiency can improve wellbeing, mood,69,70,133 and?in women?libido,69 and opens up the prospect of improving quality of life for patients with chronic adrenal insufficiency." AI Seminar published paper Link to comment Share on other sites More sharing options...
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