Case Detection of Cushing Syndrome in Adults
Endogenous Cushing syndrome (CS) or hypercortisolism is a rare condition with an incidence of 1 to 2.5 cases per 1 million persons per year in the United States. CS is associated with increased morbidity and death. The typical clinical features of hypercortisolism include:
?Central weight gain
?Easy bruising
?Facial plethora and rounding of the face (moon facies)
?Emotional lability
?Insomnia
?Proximal muscle weakness
?Supraclavicular fullness
?Dorsocervical fat pad
?Amenorrhea
?Hypertension
?Hyperglycemia
?Osteopenia or osteoporosis