How to use these boards
Using this forum is very simple. Select a topic and enter your comments--that's all there is to it! Other users will read your remarks and post their replies and offer suggestions and encouragement.
We do not dispense medical advice here or endorse any specific doctors or medical institutions. We also do not endorse the views and opinions expressed on this forum.
Before considering any treatment that affects your health, consult your doctor or qualified medical personnel.
Many members have worked hard to establish April 8 (Dr. Harvey Cushing's Birthday) as Cushing's Awareness Day. This area includes several threads such as: about the proclamation, itself; what you can do to promote that day; list of people to contact before the 8th; and other helpful info.
We all need a break every now and then from talking about testing, symptoms and surgery. We can use this area to post humor, funny stories, recipes, just chatter...anything that will take our minds of medical troubles and lighten our days
Today we remember Janice who died on this date in 2001.
Our dear friend, Janice died this past Tuesday, September 4, 2001. I received an IM from her best friend Janine, tonight. Janine had been reading the boards, as Janice had told her about this site, and she came upon my name and decided to IM me. I am grateful that she did. She said that she knew that Janice would want all of us to know that she didn't just stop posting.
Steve, Ectopic Bio
Steve was undiagnosed for 12 years. After a pituitary surgery, he turned out to have ectopic Cushing's in his right lung.
Read more at https://cushingsbios.com/2018/08/05/steve-ectopic-bio/
Night Cortisol Levels for Diagnosing Cushing’s Syndrome Less Accurate in Clinical Practice
In healthy individuals, the levels of cortisol — a steroid hormone secreted by the adrenal glands — go through changes over a 24-hour period, with the lowest levels normally detected at night.
But this circadian rhythm is disrupted in certain diseases such as Cushing’s syndrome, where night cortisol levels can be used as a diagnostic tool.
Among the tests that can be used to detect these levels are late-night serum cortisol (LNSeC) and late-night salivary cortisol (LNSaC) tests. Since it uses saliva samples, LNSaC is more practical and does not require hospitalization, so it is often recommended for the diagnosis of Cushing’s syndrome.
Read more at https://cushieblog.com/2018/08/05/night-cortisol-levels-for-diagnosing-cushings-syndrome-less-accurate-in-clinical-practice/
MEKT1 Could Be a Potential New Therapy for Treating Cushing’s Disease
PPAR-γ agonists — agents that activate PPAR-γ — include the medications rosiglitazone and pioglitazone, both of which are used to treat type 2 diabetes. Some studies have shown that rosiglitazone and pioglitazone have an effect on Pomc suppression, which would lead to lower levels of ACTH and help treat patients with Cushing’s disease.
However, the benefits of PPAR-γ agonists in the treatment of Cushing’s disease are still controversial.
Read more at https://cushieblog.com/2018/08/02/mekt1-could-be-a-potential-new-therapy-for-treating-cushings-disease/
Danielle had suddenly gained more than 20kg, found herself losing hair, constantly breaking bones and struggling to sleep.
Making matters worse, the young mother became severely depressed and noticed an unusual-looking ‘hump’ on her back.
Read more at https://cushingsbios.com/2018/07/28/danielle-g-pituitary-bio/