How to use these boards
Using this forum is very simple. Select a topic and enter your comments--that's all there is to it! Other users will read your remarks and post their replies and offer suggestions and encouragement.
We do not dispense medical advice here or endorse any specific doctors or medical institutions. We also do not endorse the views and opinions expressed on this forum.
Before considering any treatment that affects your health, consult your doctor or qualified medical personnel.
Many members have worked hard to establish April 8 (Dr. Harvey Cushing's Birthday) as Cushing's Awareness Day. This area includes several threads such as: about the proclamation, itself; what you can do to promote that day; list of people to contact before the 8th; and other helpful info.
We all need a break every now and then from talking about testing, symptoms and surgery. We can use this area to post humor, funny stories, recipes, just chatter...anything that will take our minds of medical troubles and lighten our days
Steve, Ectopic Bio
Steve was undiagnosed for 12 years. After a pituitary surgery, he turned out to have ectopic Cushing's in his right lung.
Read more at https://cushingsbios.com/2018/08/05/steve-ectopic-bio/
Night Cortisol Levels for Diagnosing Cushing’s Syndrome Less Accurate in Clinical Practice
In healthy individuals, the levels of cortisol — a steroid hormone secreted by the adrenal glands — go through changes over a 24-hour period, with the lowest levels normally detected at night.
But this circadian rhythm is disrupted in certain diseases such as Cushing’s syndrome, where night cortisol levels can be used as a diagnostic tool.
Among the tests that can be used to detect these levels are late-night serum cortisol (LNSeC) and late-night salivary cortisol (LNSaC) tests. Since it uses saliva samples, LNSaC is more practical and does not require hospitalization, so it is often recommended for the diagnosis of Cushing’s syndrome.
Read more at https://cushieblog.com/2018/08/05/night-cortisol-levels-for-diagnosing-cushings-syndrome-less-accurate-in-clinical-practice/
MEKT1 Could Be a Potential New Therapy for Treating Cushing’s Disease
PPAR-γ agonists — agents that activate PPAR-γ — include the medications rosiglitazone and pioglitazone, both of which are used to treat type 2 diabetes. Some studies have shown that rosiglitazone and pioglitazone have an effect on Pomc suppression, which would lead to lower levels of ACTH and help treat patients with Cushing’s disease.
However, the benefits of PPAR-γ agonists in the treatment of Cushing’s disease are still controversial.
Read more at https://cushieblog.com/2018/08/02/mekt1-could-be-a-potential-new-therapy-for-treating-cushings-disease/
Danielle had suddenly gained more than 20kg, found herself losing hair, constantly breaking bones and struggling to sleep.
Making matters worse, the young mother became severely depressed and noticed an unusual-looking ‘hump’ on her back.
Read more at https://cushingsbios.com/2018/07/28/danielle-g-pituitary-bio/
Transsphenoidal Surgery Is Safe and Effective Treatment for Cushing’s Disease
Surgical removal of tumors in the pituitary gland of the brain remains the gold standard for Cushing’s disease treatment.
Transsphenoidal surgery (TSS) usually leads to good remission rates ranging from 68-95%, depending on the location and type of tumor, the neurosurgeon’s expertise, follow-up period, and the definition of remission.
Today, TSS consists of surgery directed through the nose to get to the bottom of the skull, where the pituitary gland is located. The tumor is reached via the nasal cavity with no need for incisions on the face.