How to use these boards
Using this forum is very simple. Select a topic and enter your comments--that's all there is to it! Other users will read your remarks and post their replies and offer suggestions and encouragement.
We do not dispense medical advice here or endorse any specific doctors or medical institutions. We also do not endorse the views and opinions expressed on this forum.
Before considering any treatment that affects your health, consult your doctor or qualified medical personnel.
Many members have worked hard to establish April 8 (Dr. Harvey Cushing's Birthday) as Cushing's Awareness Day. This area includes several threads such as: about the proclamation, itself; what you can do to promote that day; list of people to contact before the 8th; and other helpful info.
We all need a break every now and then from talking about testing, symptoms and surgery. We can use this area to post humor, funny stories, recipes, just chatter...anything that will take our minds of medical troubles and lighten our days
Etomidate Found Effective in Severe Cushing’s Syndrome
In April 2017, the patient arrived at the emergency room with sepsis — a potentially life-threatening complication of an infection — that originated in the gut.
Because ketoconazole had failed to lower cortisol levels, the patient started receiving infused etomidate, an inhibitor of the enzyme 11‐beta‐hydroxylase that prevents cortisol synthesis.
This treatment was stopped one day before the bilateral removal of the adrenal glands as a definitive treatment for the elevated production of cortisol.
Read more at https://cushieblog.com/2018/05/18/etomidate-found-effective-in-severe-cushings-syndrome/
Register now for the 10th Annual Johns Hopkins Pituitary Patient Day
Saturday, October 13, 2018, 9:00 a.m. to 3:00 p.m.
More info at https://cushieblogger.com/2018/05/18/tenth-annual-johns-hopkins-pituitary-patient-day/
Based on long-term patient outcomes, researchers were able to identify six categories of common diagnostic and surgical failures. They include:
persistently high cortisol levels despite the successful removal of lesions
the failure of tumor resection
recurrence of disease
a failure to identify the source of ACTH secretion
the absence of identifiable lesions during exploratory surgery
Read more at https://cushieblog.com/2018/05/16/study-describes-6-common-surgical-failures-in-cushings-disease-treatment/
Every ache or pain or out of the ordinary experience triggers anxiety. I am 7 years post op. I don’t have panic attacks per se, but I do get upset and frightened. These feelings also occur when the doctor sends me for routine testing just to make sure there is no relapse...
In the comments area of https://cushieblogger.com/2018/05/11/guest-question-ptsd-and-cushings/
Relacorilant, an investigational therapy developed by Corcept Therapeutics, may effectively manage the effects of excess cortisol in patients with Cushing’s syndrome, interim data from an ongoing Phase 2 trial show.
In particular, the treatment significantly improved sugar tolerance and the levels of osteocalcin, a bone growth biomarker commonly suppressed by excess cortisol.
Read more at https://cushieblog.com/2018/05/12/relacorilant-effectively-manages-cortisol-effects-in-cushings-patients/